Journal of Wound Care

In August’s edition of JWC, we feature two systematic reviews: one on measuring subepidermal moisture to detect early pressure ulcer development, and the other on health-related quality of life and assessment in patients with lower limb lymphoedema. A preclinical study examines the role of mast cells in cellular modifications evoked by Exendin-4 in treated wounds in mice, and a randomised controlled trial evaluates the use of low-frequency contact ultrasonic debridement with and without polyhexamethylene biguanide in hard-to-heal leg ulcers. The PICO-1 study on the local physiological effects of a single-use topical negative pressure device in healthy volunteers is presented, and a pilot study evaluates wound tissue segmentation by computerised image analysis of clinical pressure injury photographs. An overview of the evidence of the importance of periwound skin in wound healing is described, and the prevalence of skin lesions and associated factors in hospitalised adult patients with cancer is detailed. The value of administering intravenous antibiotics during haemodialysis in the treatment of diabetic foot infections is the focus of an observational study. This month also features the World Union of Wound Healing Societies’ supplement, which features two animal models: one examining the effect of bromelain on mast cell numbers and degranulation in diabetic rat wound healing; the other, a stereological and molecular study of the effects of Feijoa sellowiana fruit extract on wound healing in rats. The use of polyvinyl alcohol-ionic hydrogels containing a wound healing agent to manage wounds in different environments is evaluated. A case study on meticillin-susceptible Staphylococcus aureus pyomyositis and cellulitis in the right thigh of a 15-year-old boy is presented, as well as a histopathological examination of the longitudinal physiological remoulding of lower limb skin as a cause of diabetic foot ulcer.